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Tramadol dependency: what to know and where to get support

Despite being a legally prescribed drug, Tramadol dependence is a serious condition that can develop under certain conditions.

Start your recovery today with Priory’s expert-led tramadol addiction treatment, designed to support you on the path to a drug-free future.

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Page last updated:
Written by: Anna Drescher
Mental health & addictions writer
Clinically reviewed by: Rupert Turner
Lead Addiction Therapist at Priory Hospital Woking

Tramadol is an opioid medication that’s usually prescribed for moderate to severe pain, for example, after an operation or injury. It can be highly effective in treating short-term and chronic pain, but it comes with risks that many people aren’t aware of, including dependence, overdose, and physical and mental health issues. 

If you’re concerned about yours or a loved one’s use of tramadol, help is available. With the right support, it’s possible to recover from prescription drug addiction.

Common signs and symptoms of tramadol addiction

Tramadol addiction, which is a form of opioid dependency, causes a range of symptoms that vary based on individual circumstances, such as the dose of tramadol you're taking, and how frequently you're taking it. Common indicators of tramadol addiction include:

  • Tolerance development: needing higher doses of tramadol to feel the same effects
  • Withdrawal symptoms: experiencing physical symptoms like nausea, sweating, tremors, and irritability when tramadol use is reduced or stopped
  • Increased use over time: consuming tramadol more frequently or in larger amounts than intended
  • Intense cravings: strong desires or urges to use tramadol
  • Inability to function without tramadol: feeling unable to manage daily tasks or responsibilities without the drug
  • Continued use despite negative consequences: persisting with tramadol use even after experiencing harmful effects on mental and emotional health
  • Doctor shopping: visiting multiple doctors to obtain more tramadol prescriptions
  • Prescription mismanagement: frequently reporting lost prescriptions or taking tramadol more rapidly than prescribed
  • Forging and stealing prescriptions: engaging in illegal activities to acquire more tramadol
  • Online purchases: buying tramadol over the internet, often without medical oversight
  • Impact on personal, social and work life: tramadol use affecting relationships, social interactions and job performance

Timeline of tramadol addiction

Tramadol addiction often starts with legitimate medical use that changes over time. Understanding the stages of tramadol addiction can help you to recognise it early and take steps to regain control.

Prescribed use

You’re prescribed tramadol for pain relief and take it as prescribed by your doctor. At this stage, it’s providing relief and improving your quality of life.

Tolerance builds

Tramadol targets opioid receptors in the brain, which become less sensitive over time, so the same dose produces less effect.

This is a normal physical response but can lead some people to take it more often and at a higher dose to get the same pain relief.

At this stage, the early warning signs of addiction may start to show.

Using it for more than pain

Tramadol increases serotonin and noradrenaline, which can lift your mood, reduce anxiety, make you feel euphoric, and relaxed.

These effects might encourage you to keep taking tramadol, even when your pain has subsided, to manage stress, painful experiences or emotional discomfort.

Dependence develops

Prolonged, excessive use builds tolerance. When you stop taking it, you develop unpleasant symptoms such as restlessness, anxiety, trouble sleeping or shivers.

To avoid these symptoms, you keep taking it, which can lead to a cycle of abuse.

Addiction

The signs and symptoms of addiction are present. You no longer feel in control. You feel an overwhelming urge to take tramadol, spend a lot of time thinking about it, hide your use, and can’t stop taking it even if you want to.

Withdrawing from tramadol

Tramadol withdrawal happens when your body has become dependent on the drug, and you stop or reduce your use.

While your body is readjusting to functioning without the drug, it can lead to a range of very uncomfortable and sometimes dangerous symptoms.

Typical withdrawal symptomsAtypical withdrawal symptoms
Severe cravingsSevere anxiety
AnxietyPanic attacks
Low moodConfusion
Sleep disturbancesParanoia
Sweating, chills or goosebumpsDepersonalisation (feeling outside yourself)
Flu-like symptomsDerealisation (feeling disconnection from surroundings)
Aches and painsHallucinations
Nausea, vomiting and diarrhoea
Tremors and palpitations

How long does tramadol withdrawal last?

The timeline and duration of tramadol withdrawal varies depending on how much you’ve been taking, how long you’ve been taking it, and personal factors like metabolism.

A typical timeline might looks like:

Immediate withdrawal (8 to 24 hours after last dose)

Symptoms such as cravings, anxiety, restlessness, sweating, runny nose, and sleep disruption are common.

Acute withdrawal (2 to 3 days)

Symptoms usually peak during the first few days after last taking tramadol and include aches, gastrointestinal problems, uncontrollable shaking, insomnia, irritability and strong cravings. They tend to ease after the first week.

In severe cases, you might develop hallucinations, seizures and delirium tremens (sudden and severe changes to the nervous system). If these symptoms develop, you should seek immediate medical attention.

Post-acute withdrawal (after the first week)

Withdrawal symptoms start to improve but some people may experience lingering anxiety or sleep disturbances.

In rare cases, you might develop post-acute withdrawal syndrome (PAWS), which can leave some withdrawal symptoms lingering for weeks or months later.

Why safe detox matters

Abruptly stopping tramadol can trigger intensely uncomfortable (and sometimes dangerous) withdrawal symptoms. Working with a medical professional to create a plan for safely coming off tramadol reduces the risks associated with withdrawal.

Tramadol withdrawal can be managed safely through a drug detox, as healthcare professionals can monitor your symptoms in a comfortable and supportive environment.

Side effects of tramadol

Prolonged and excessive tramadol use can have serious and long-term side effects, including physical, mental and emotional consequences.

Physical health effects

  • Heightened pain sensitivity, know as hyperalgesia
  • Gastrointestinal problems
  • Hormonal changes – causing things like low libido, erectile dysfunction, menstrual irregularities, low energy and low mood
  • Seizures
  • Serotonin syndrome  - symptoms include agitation, loss of control over body movement, increased sweating, diarrhoea, fever and confusion
  • Shallow or slow breathing
  • Risk of overdose

Mental and emotional effects

Tramadol alters serotonin and noradrenaline functioning in the brain and may consequently have mild to severe mental and emotional effects, including:

  • Low mood  - feeling flat, on edge or tearful, especially between doses
  • Cognitive impairment  - such as slowing down brain activity and problems with memory or concentration
  • Sleep disturbances
  • Severe anxiety
  • Manic symptoms  - increased energy, racing thoughts, increased rate and intensity of speech and impulsive behaviour
  • Psychotic symptoms  - paranoia, losing touch with reality and hallucinations
  • Risk of suicide  – in these cases, seek urgent crisis support 
    If you develop severe symptoms such as seizures, breathing difficulties, seek urgent help by calling 999.

Treatment for tramadol addiction

Tramadol addiction is a serious condition but with the right support, it can be treated and it’s possible to make a full recovery.

At Priory, we offer evidence-based treatment tailored to your individual needs and goals.

Depending on your needs, our addiction treatment services could include a medically supported detox, therapy, residential stays and relapse prevention support.

Medically supported detox

With the support of highly qualified clinicians, medical detox helps you to come off tramadol safely.

Withdrawal symptoms are managed in a comfortable environment and often with the help of evidence-based medication.

Psychological therapies

Therapy is fundamental to recovery as it gives you the chance to understand what drives your addiction and build healthier ways of coping. You learn strategies to stay on track and reduce the risk of relapse so that your progress lasts well into the future.

At Priory, we offer a range of evidence-based approaches, including:

  • Cognitive behavioural therapy (CBT): helps you identify and change unhelpful thoughts and behaviours around tramadol and build healthier coping mechanisms.
  • Dialectical behaviour therapy (DBT): teaches you skills for managing intense emotions, stress, and urges. It’s especially helpful for those with underlying mental health conditions.
  • Trauma-informed therapy: explores how past experiences/trauma may be contributing to addiction.
  • One-to-one therapy: a confidential, supportive space to causes of addiction and create a personalised plan.
  • Group therapy: offers a space to connect with other in recovery. You learn and practise skills and share insights together, giving you a sense of community and empowerment.

Relapse prevention

Relapse is a common part of recovery from any drug addiction.

To reduce the risk of relapse, you’ll work with therapists to identify your personal triggers and create strategies for cravings, stress, and emotional setbacks.

This can include grounding techniques, thought-reframing, urge-surfing, and a written relapse recovery plan or toolkit you can use in your daily life.

Peer support

Many people benefit from taking part in 12-step programmes (such as Narcotics Anonymous), SMART Recovery, or in-house groups.

Peer communities offer accountability, shared experience and encouragement, and knowing you’re not alone can be invaluable to your recovery.

Aftercare and ongoing support

Addiction recovery is a lifelong process so it’s crucial that you receive ongoing support after the initial treatment is completed. That’s why at Priory, we offer 12 months of free aftercare, which may include weekly groups, alumni events, one-to-one sessions, and relapse-prevention refreshers. Digital options are also available at some locations.

If you’re ready to make the first step in your recovery, Priory offers a free confidential addiction assessment to match you with the right level of support.

FAQs

Can you get addicted to tramadol if it’s prescribed by your doctor?

Yes, but your doctor will be monitoring your use and dosage to limit the risk of an addiction developing. It is important to be honest with your doctor about any past history of addiction, check in about how you’re getting on with the medication regularly and if in any doubt, get a second opinion.  

What’s the difference between tramadol and other opioids?

Tramadol is a weaker opioid than morphine or oxycodone but still risky. It acts on opioid receptors and blocks serotonin/noradrenaline reuptake, like some antidepressants. This may mean milder pain relief, but addiction risk remains, especially with higher doses or long-term use.

Can I come off tramadol without professional help?

It’s not recommended you come off tramadol without medical guidance from an addiction specialists like Priory. Stopping tramadol suddenly (‘cold turkey’) can trigger severe withdrawal and increase the risk of relapse or overdose after lost tolerance. 

How do I support someone who might be addicted to tramadol?

If you suspect tramadol abuse or addiction, start a gentle conversation. Avoid blame, ask open questions, and listen. Encourage seeking help from a GP or a confidential Priory assessment. Protect yourself with boundaries and support. Call 999 or go to A&E if symptoms include severe agitation, confusion, breathing problems, seizure, chest pain, or suicidal thoughts. 

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